Cross-linked polysaccharide drug carrier
US6303585A · kind A · utility
50Cited by
5References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 1, 1998 |
| Grant date | Oct 16, 2001 |
| Priority date | — |
| Expiry date | Jul 1, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08B37/0063
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A carrier and a method for preparing it are provided for use in the delivery of therapeutic agents. A polysaccharide is reacted with an oxidizing agent to open sugar rings on the polysaccharide to form aldehyde groups. The aldehyde groups are reacted to form covalent oxime linkages with a second polysaccharide and each of the first and second polysaccharide is selected from the group consisting of hyaluronic acid, dextran, dextran sulfate, chondroitin sulfate, dermatan sulfate, keratan sulfate, heparan, heparan sulfate and alginate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.