3-thienyl and 3-furanyl pyrrolidine modulators of chemokine receptor activity
US6303593A · kind A · utility
5Cited by
1References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 1, 2000 |
| Grant date | Oct 16, 2001 |
| Priority date | — |
| Expiry date | Mar 1, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is directed to pyrrolidine compounds of the formula I: ##STR1## PA1 (wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4c, R.sup.4d, and R.sup.4f are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-3 and/or CCR-5.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.