Patent · US Expired

Aminoindan derivatives

US6303650A · kind A · utility

17Cited by
1References
40Claims
0Family size

Assignees

Inventors

Key dates

Filing dateJun 18, 1999
Grant dateOct 16, 2001
Priority date
Expiry dateJun 18, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2602/10
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This invention is directed to compounds of the following formula ##STR1## wherein when a is O, b is 1 or 2; when a is 1, b is 1, m is from 0-3 X is O or S, Y is halogeno, R.sub.1 is hydrogen C.sub.1-4 alkyl, R.sub.2 is hydrogen, C.sub.1-4 alkyl, or optionally substituted propargyl and R.sub.3 and R.sub.4 are each independently hydrogen, C.sub.1-8 alkyl, C.sub.6-12 aryl, C.sub.6-12 aralkyl each optionally substituted. This invention is also directed to the use of these compounds for treating depression, Attention Deficit Disorder (ADC), Attention Deficit and Hyperactivity Disorder (ADHD), Tourette's Syndrome, Alzheimer's Disease and other dementia's such as senile dementia, dementia of the Parkinson's type, vascular dementia and Lewy body dementia. This invention is further directed to a pharmaceutical composition comprising a therapeutically effective amount of the above-defined compounds and a pharmaceutically acceptable carrier.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.