Nucleic acids encoding narbonolide polyketide synthase enzymes from streptomyces narbonensis
US6303767A · kind A · utility
20Cited by
4References
9Claims
0Family size
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Key dates
| Filing date | Nov 5, 1999 |
| Grant date | Oct 16, 2001 |
| Priority date | — |
| Expiry date | Nov 5, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/52
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Host cells comprising recombinant vectors encoding the narbomycin polyketide synthase and narbomycin modification enzymes from Streptomyces narbonensis can be used to produce narbomycin, picromycin, methymycin, and neomethymycin. Recombinant DNA constructs comprising one or more narbomycin polyketide synthase domains, modules, open reading frames, and variants thereof can be used to produce recombinant polyketide synthases and a variety of different polyketides with application in agriculture, medicine, and animal health.
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