Systems and methods for imaging fluorophores
US6304771A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 15, 1997 |
| Grant date | Oct 16, 2001 |
| Priority date | — |
| Expiry date | Jan 15, 2017 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/4795
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The systems comprise source means for illuminating the fluorophores with diffuse photon density waves of a first specified wavelength, whereby the fluorophores will fluoresce re-radiated diffuse photon density waves of a second wavelength after being illuminated with the diffuse photon density waves of the first specified wavelength; detection means for detecting the re-radiated diffuse photon density waves of the second wavelength, wherein there is a phase shift between the diffuse photon density waves of the first wavelength and the diffuse photon density waves of the second wavelength; and processing means interfaced with the detection means for processing data corresponding to the phase shift and the amplitude of the re-radiated waves to determine concentration and lifetime of the fluorophores as a function of spatial position of the fluorophores in the turbid medium.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.