Injectable naltrexone microsphere compositions and their use in reducing consumption of heroin and alcohol
US6306425A · kind A · utility
56Cited by
14References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 7, 2000 |
| Grant date | Oct 23, 2001 |
| Priority date | — |
| Expiry date | Apr 7, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/36
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An injectable slow-release naltrexone formulation is provided comprising naltrexone in a poly(D,L-lactide) matrix with a small amount of residual ethyl acetate. Upon intramuscular injection of the composition, naltrexone is released in a controlled manner over an extended period of time. The composition finds use in the treatment of heroin addicts and alcoholics to reduce consumption of the abused substances.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.