Template-directed photoligation
US6306587A · kind A · utility
52Cited by
0References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 10, 1997 |
| Grant date | Oct 23, 2001 |
| Priority date | — |
| Expiry date | Nov 10, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6827
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Methods, apparatus and compositions are presented for ligating ligands together which bind to a common receptor. One embodiment includes polynucleotide probes having photoreactive functional groups. The probes are capable of assuming substantially contiguous reactive positions on a target polynucleotide placing the photoreactive group in juxtaposition. Activation of the photoreactive functional groups with radiant energy form a probe reaction product in which the probes are bound to each other.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.