Condensed purine derivatives
US6306847A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 5, 1998 |
| Grant date | Oct 23, 2001 |
| Priority date | — |
| Expiry date | Jun 5, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P11/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides condensed purine derivatives or pharmacologically acceptable salts thereof exhibiting adenosine A.sub.3 acceptor antagonising activity, and having an antiasthmatic action, a bronchodilator action, an antiantiitching action, etc., and represented by the following formula (I): ##STR1## (wherein R.sup.1 represents substituted or unsubstituted aryl or a substituted or unsubstituted aromatic heterocyclic group; R.sup.2 represents hydrogen, lower alkyl, alicyclic alkyl, substituted or unsubstituted aralkyl, substituted or unsubstituted aryl, or a substituted or unsubstituted aromatic heterocyclic group; R.sup.3 represents hydrogen, lower alkyl, or substituted or unsubstituted aralkyl; X.sup.1 and X.sup.2 are the same or different and each represents hydrogen, lower alkyl, substituted or unsubstituted aralkyl, or substituted or unsubstituted aryl; and n represents an integer of 0 to 3).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.