Rapid purification by polymer supported quench
US6306959A · kind A · utility
7Cited by
16References
13Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 15, 1998 |
| Grant date | Oct 23, 2001 |
| Priority date | — |
| Expiry date | Oct 15, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/817
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
Novel polymer-supported quenching reagents of Formula (I): P-L-Q, wherein P is a polymer of low chemical reactivity which is soluble or insoluble; Q is one or more quenching reagents, or an acid or base addition salts thereof, that are capable of selective covalent reaction with unwanted byproducts, or excess reagents; and L is one or more chemically robust linkers that join P and Q; are described, as well as methods for their preparation and methods for their use in the rapid purification of synthetic intermediates and products in organic synthesis, combinatorial chemistry and automated organic synthesis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.