Substituted aurone derivatives
US6307070A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 24, 1998 |
| Grant date | Oct 23, 2001 |
| Priority date | — |
| Expiry date | Jul 24, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/83
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for treating a fungal infection is disclosed. The method includes administering to a patient a pharmaceutical composition containing a compound of formula (IA): ##STR1## where each R is independently H, OH, Br, Cl, I, amino, thiol, nitro, C.sub.1-4 alkoxy, C.sub.1-4 alkenyloxy, C.sub.2-6 alkoxyalkyleneoxy, C.sub.1-4 alkylthio, C.sub.3-18 alkyl, or C.sub.3-18 alkenyl; or two adjacent R's, taken together, are a C.sub.2-18 bivalent moiety containing at least one oxgen atom, substituted or disubstituted with A or B or both, A being H, OH, Br, Cl, I, amino, or thiol, and B being H, C.sub.1-10 alkyl, C.sub.2-18 alkenyl, or C.sub.6-18 aryl; provided at least two Rs are not H; X is C.sub.4-10 alkyl, C.sub.4-20 alkenyl, or a C.sub.4-20 single, C.sub.6-20 bridged, or C.sub.6-20 fused ring moiety containing cycloalkyl, cycloalkenyl, aryl, heterocycle, or heteroaryl, where X is substituted with H, OH, Cl, Br, I, amino, cyano, nitro, alkyl, alkoxy, alkenyl, or alkenyloxy; provided that if X is a heteroaryl or heterocyclic moiety where two Rs are each OH and meta to each other, then the remaining R is H and ortho to each of the two hydroxyls, and Y and Z are each O and a ring atom of X …
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.