Process for substituted 3-hydroxybutyrate esters

US6307094A · kind A · utility

Inventors

• Joshua Anthony Chong · Lansdale, US
• Fereydon Abdesaken · Dresher, US
• Lori Ann Spangler · Nazareth, US
• Renee Caroline Roemmele · Masontown, US
• Randall Wayne Stephens · Perkasie, US
• Peter D. Nightingale · Dallas, US
• David Hartley · Ware, GB

Key dates

• Filing date: May 2, 2000
• Grant date: Oct 23, 2001
• Expiry date: May 2, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C67/31
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention provides a solventless process for the catalytic hydrogenation of esters of 4,4,4-trihaloacetoacetic acid using a platinum catalyst in the presence of an acid or base co-catalyst to provide the analagous 3-hydroxybutyrate ester. Such 3-hydroxybutyrate esters are useful as solvents, cleaners or fine chemical intermediates.