Method of preventing neuronal death
US6310093A · kind A · utility
3Cited by
3References
16Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 27, 1998 |
| Grant date | Oct 30, 2001 |
| Priority date | — |
| Expiry date | Aug 27, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/185
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is a method for preventing neuronal cell death subsequent to an injury to neuronal tissue, particularly central nervous tissue exposed to an ischemic or hypoxic event, to trauma or to a chronic neurodegenerative disorder. The method includes exposing the cells to a glutaminase inhibitor that is relatively impermeant to healthy, intact cell membranes, and which is preferably a specific inhibitor of the form of glutaminase that is widely present in brain tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.