5,5-bis(difluoramino)hexahydro-1,3-dinitropyrimidine (RNFX) and certain electronegatively substituted pyrimidines
US6310204A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 16, 2000 |
| Grant date | Oct 30, 2001 |
| Priority date | — |
| Expiry date | Feb 16, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D239/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Calculated performance improvements are expected from a particularly new class of compounds, geminal-bis(difluoramino)-substituted heterocyclic nitramines, when formulated into explosives and propellants. This invention involves novel and nonintuitive methods for the preparation of certain derivatives of 2,2-bis(difluoramino)-N-nitro-1,3-propanediamine which are suitable precursors leading to 5,5-bis(difluoramino)hexahydro-1,3-dinitropyrimidine (RNFX). The invention also involves novel and nonintuitive methods for the preparation of RNFX, a specific member of a general class of compounds with the substructure 2,2-bis(difluoramino)-N-nitro-1,3-propanediamine. RNFX is produced by the use of key intermediates, including tetrahydropyrimidin-5(4H)-ones, which allow formation of the target structural subcomponent, 2,2-bis(difluoramino)-N-nitro-1,3-propanediamine, and a more specific substructure of 2,2-bis(difluoramino)-N,N'-dinitro-1,3-propanediamine. The method of making RNFX, generally, comprises reacting with a difluoramine source, a tetrahydro-1,3-disulfonylpyrimidin-5(4H)-one; reacting with a nitronium source, the resultant 5,5-bis(difluoramino)hexahydro-1,3-disulfonylpyrimidine; N…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.