Special 3-azabicyclo[3.1.0]hexanes, method for producing and modifying the same, and their use

US6310216A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Elmar Vilsmaier · Otterbach, DE
• Torsten Goerz · Hochspeyer, DE
• Gunther Milch · Kaiserslautern, DE
• Uwe Petersen · Leverkusen, DE
• Axel Dalhoff · Wuppertal, DE
• Gabriele Schmuck · Wuppertal, DE

Key dates

• Filing date: Feb 18, 2000
• Grant date: Oct 30, 2001
• Expiry date: Feb 18, 2020

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/55
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

6-Amino-3-azabicyclo[3.1.0]hexanes of the formula ##STR1## wherein R.sup.1 and R.sup.2 independently of one another are C.sub.3 -C.sub.4 -alkenyl or Ar--CH(R')-- where R' is hydrogen or C.sub.1 -C.sub.4 -alkyl and Ar is an optionally substituted C.sub.6 -C.sub.10 -aryl and R.sup.3 is hydrogen, C.sub.3 -C.sub.4 -alkenyl, Ar--CH(R')-- where R' is hydrogen or C.sub.1 -C.sub.4 -alkyl and Ar is an optionally substituted C.sub.6 -C.sub.10 -aryl or COOR.sup.4 where R.sup.4 is C.sub.1 -C.sub.4 -alkyl or C.sub.2 -C.sub.4 -alkenyl. The invention also relates to a method for making these compounds and a method for using them.