Patent · US Expired

Methods of treatment using cytokine synthesis inhibitory factor

US6312680A · kind A · utility

1Cited by

0References

20Claims

0Family size

Inventors

Timothy Mosmann · Atherton, US
Kevin W. Moore · Palo Alto, US
Martha W. Bond · Palo Alto, US
Paulo J. M. Vieira · Mountain View, US

Key dates

Filing date	Jun 5, 1995
Grant date	Nov 6, 2001
Priority date	—
Expiry date	Jun 5, 2015

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S930/141
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Mammalian genes and proteins, designated cytokine synthesis inhibitory factors (CSIFs now known as Interleukin-10 (IL-10)), are provided which are capable of inhibiting the synthesis of cytokines associated with delayed type hypersensitivity responses, and which, together with antagonists, are useful in treating diseases associated with cytokine imbalances, such as leishmaniasis and other parasitic infections, and certain immune disorders including MHC associated autoimmune diseases caused by excessive production of interferon-.gamma..

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.