Retroviral vectors
US6312682A · kind A · utility
40Cited by
1References
71Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 28, 1998 |
| Grant date | Nov 6, 2001 |
| Priority date | — |
| Expiry date | Dec 28, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16052
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Retroviral vector production systems for producing lentivirus-based vector particles which are capable of infecting and transducing non-dividing target cells, wherein one or more of the auxiliary genes such as vpr, vif, tat, and nef in the case of HIV-1 are absent from the system. The systems and resulting retrovirus vector particles have improved safety over existing systems and vectors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.