Method of using a crystal of the N-terminal domain of a signal transducer and activator of transcription
US6312887A · kind A · utility
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16Claims
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Key dates
| Filing date | Apr 24, 2000 |
| Grant date | Nov 6, 2001 |
| Priority date | — |
| Expiry date | Apr 24, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/4705
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a crystal containing the N-terminal domain of a STAT protein that is of sufficient quality to perform X-ray crystallographic studies. Methods of preparing the crystals are include in the invention. The present invention further discloses the three-dimensional structure of the crystal. The present invention also provides methods of using the structural information in drug discovery and drug development.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.