Multistage electromagnetic separator for purifying cells, chemicals and protein structures
US6312910A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 10, 2000 |
| Grant date | Nov 6, 2001 |
| Priority date | — |
| Expiry date | Apr 10, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K1/24
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A multistage electromagnetic separator is designed to separate magnetically susceptible materials suspended in fluids. The apparatus includes an upper plate and a lower plate set to a fill position and the fluid samples are filled into upper and lower cuvettes. The upper cuvette rotates into position above the lower cuvette aligning the upper and lower cuvettes. A translating electromagnet energizes to a programmed current level and translates from the bottom of the lower cuvette to the interface of the plates. The translating electromagnet is de-energized, and a holding electromagnet is energized to a programmed current level pulling particles within a specified mobility range into the top of the captured upper collection cuvette. The holding electromagnet is de-energized leaving the permanent holding magnet to keep the collected sample particles in the top cuvette while the upper plate rotates thereby capturing the sample of the collected particles. The process can be preprogrammed to vary or remain the same for a plurality of capture cuvettes. The apparatus and method of use provides a method for quantitatively separating cells, proteins, or other particles, using multistage, ma…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.