Cathepsin-L, the pre-proform thereof and the corresponding propeptide from ciliates

US6312935A · kind A · utility

Assignees

• Hoechst Research & Technology · DE
• DEUTSCHLAND GMBH & CO. KG · DE

Inventors

• Thomas Kiy · Frankfurt, DE
• Joachim Schultz · Herrenberg, DE

Key dates

• Filing date: Apr 13, 1998
• Grant date: Nov 6, 2001
• Expiry date: Apr 13, 2018

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to the isolation of the prepro form of cathepsin L, of its leader sequence, of cathepsin L and of the affiliated propeptide from ciliates, in particular Paramecium, to the use of these peptides and to a process for preparing cathepsin L from ciliates.