Organic compounds

US6313344A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Stephan Trah · Chur, CH
• Henry Szczepanski · Möhlin, CH
• Ottmar Franz Huter · Bad Kötzting, DE
• Roger Graham Hall · Chur, CH
• Saleem Farooq · Aesch, CH
• Alfons Pascual · Basel, CH

Key dates

• Filing date: May 27, 1998
• Grant date: Nov 6, 2001
• Expiry date: May 27, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/4021
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of formula ##STR1## (I), wherein PA1 either X is CH or N, Y is OR.sub.1 and Z is O, or PA1 X is N, Y is NHR.sub.8 and Z is O, S or S(.dbd.O); PA1 R.sub.1, R.sub.2 and R.sub.3 are as defined according to the specification; m is 0, 1 or 2; PA1 R.sub.5 is, for example, halogen, C.sub.1 -C.sub.6 alkyl, halo-C.sub.1 -C.sub.6 alkyl or C.sub.3 -C.sub.6 cycloalkyl; PA1 n is 0, 1, 2, 3 or 4; R.sub.9 is methyl, fluoromethyl or difluoromethyl; PA1 A and R.sub.7 are as defined according to the specification; PA1 D is O, S, --S(.dbd.O) or S(.dbd.O).sub.2 ; G is C.sub.1 -C.sub.6 aalkylene; PA1 T--R.sub.6 is R.sub.6, --C(.dbd.N--O--A.sub.1 --R.sub.77)--R.sub.6 ; --SiR.sub.14 (R.sub.15)--R.sub.6 ; --C(.dbd.O)--R.sub.6 ; --C(R.sub.16).dbd.C(R.sub.17)--R.sub.6, --C.ident.C--R.sub.6 or PA1 --D--R.sub.6 ; PA1 R.sub.6 is C.sub.1 -C.sub.4 alkyl or unsubstituted or substituted aryl or heteroaryl; PA1 A.sub.1 and R.sub.77 are as defined above for A and R.sub.7 ; PA1 L is U--R.sub.18, P(OR).sub.v R.sub.11 R.sub.12, P(S).sub.w R.sub.11 R.sub.12 or N(aryl)R.sub.13 ; v and w are 0 or 1; PA1 U--R.sub.18 is --C(.dbd.O)--C(.dbd.O)--R.sub.18 ; --C(OH)--C(OH)--R.sub.18 ; --C(.dbd.N--O--A.sub.1 --R.sub.7)…