Patent · US Expired

Devices for molecular biological analysis and diagnostics including waveguides

US6315953A · kind A · utility

32Cited by
46References
38Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 29, 1999
Grant dateNov 13, 2001
Priority date
Expiry dateJan 29, 2019

Classification

  • Technology area (CPC H)Electricity
  • CPC primaryH01L2924/0002
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

An electronic device for performing active biological operations includes a support substrate, a second substrate, a source of illumination, and an edge illumination layer. The support substrate includes first and second surfaces and a via between the first and second surfaces to permit fluid flow through the substrate. The second substrate includes a first surface that is adapted to be disposed in facing arrangement with the second surface of the first substrate. The second substrate includes an array of microlocations wherein the array is adapted to receive the fluid. A sealant is disposed between the second face of the support substrate and the first face of the second substrate. The device includes a source of illumination and an edge illumination layer having an input adapted to receive the illumination from the source, and an output adapted to direct the illumination to the array. The edge illumination layer is disposed adjacent to and between the support substrate and the second substrate. The illumination from the edge illumination layer is directed substantially parallel to the support substrate and second substrate and illuminates the array.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.