Patent · US Expired

End modified thermal responsive hydrogels

US6316011A · kind A · utility

100Cited by
7References
41Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 4, 1999
Grant dateNov 13, 2001
Priority date—
Expiry dateAug 4, 2019

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K47/34
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A pharmaceutic composition includes a pharmaceutically acceptable carrier, comprising a reverse thermally viscosifying polymer. The polymer includes a linear block copolymer, wherein at least one block comprises a poloxamer; and at least one block comprises a biocompatible polymer or oligomer, in an aqueous medium. The composition also includes an active agent which imparts a pharmaceutic or cosmetic effect. The composition viscosities in response to an environmental stimulus. The composition is suitable for administration of the pharmaceutical agent across dermal, otic, rectal, vaginal, ophthalmic, esophageal and nasal mucosal membranes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.