Method and apparatus for manufacturing tablet capable of quick disintegration in oral cavity
US6316026A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 8, 1999 |
| Grant date | Nov 13, 2001 |
| Priority date | — |
| Expiry date | Jan 8, 2019 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB30B11/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method and an apparatus are adapted to manufacture a tablet capable of quick disintegration in the oral cavity that has a sufficiently large porosity and can be disintegrated in the oral cavity in a very short period of time, typically between 3 and 5 seconds. A tablet manufactured by means of such a method and such an apparatus also constitutes part of the present invention. The method for manufacturing a tablet capable of quickly disintegration in the oral cavity comprises steps of punching a tablet out of a pharmaceutical composition containing one or more than one medicinal agents and one or more than one water-soluble saccharides under pressure between 0.20 and 0.01 t/cm.sup.2 and shaping the tablet by moisturizing and drying it, while transferring it without causing it to drop, said tablet having a porosity between 20 and 40%.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.