Isosorbide dinitrate-containing patch
US6319515A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 8, 1998 |
| Grant date | Nov 20, 2001 |
| Priority date | — |
| Expiry date | Sep 8, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to an isosorbide dinitrate-containing patch, in which an adhesive layer comprising an adhesive composition is formed on a flexible support, and the adhesive composition consists of an acrylic-based adhesive (A), a polyvinyl acetate-based adhesive (B), a plasticizing component (C) and isosorbide dinitrate (D), and satisfies the following weight ratios (1) through (3) of each of the components: PA1 (1) A:B=70:30 to 10:90, PA1 (2) the weight ratio of the component C based on the adhesive composition is 10 to 40% by weight, and PA1 (3) the weight ratio of the component D based on the adhesive composition is 20 to 35% by weight. Provided is a patch excellent in percutaneous absorption, handleability, resistance to skin irritation, sustained release, adhesivity, etc.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.