2-arylethyl-(piperidin-4-ylmethyl)amine derivatives

US6319920A · kind A · utility

Assignee

• Syntex (U.S.A.) LLC · US

Inventors

• Joan Marie Caroon · Mountain View, US
• Robin Clark · Palo Alto, US
• Michael Patrick Dillon · Mill Valley, US
• Ralph New Harris, III · Redwood City, US
• Sharathchandra S. Hegde · Sunnyvale, US
• Clara Jeou Jen Lin · Palo Alto, US
• Hans Maag · Menlo Park, US
• David Bruce Repke · Palo Alto, US

Key dates

• Filing date: Feb 1, 1999
• Grant date: Nov 20, 2001
• Expiry date: Feb 1, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to muscarinic receptor antagonist compounds selected from the group of compounds represented by Formula I: ##STR1## wherein the substituents are as defined in the specification; and their pharmaceutically acceptable salts, individual isomers or a racemic or non-racemic mixture; pharmaceutical compositions containing them; and methods for their use as therapeutic agents.