Process for the preparation of benzyl-ethers
US6320085A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 13, 1999 |
| Grant date | Nov 20, 2001 |
| Priority date | — |
| Expiry date | Jul 13, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C41/09
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
##STR1## The subject matter of the invention is the process for the preparation of mixed ethers of formula I, wherein Ar represents an aromatic or one or more heteroatom-containing moiety, optionally substituted by one or more C.sub.1-4 alkoxy, methylenedioxy, C.sub.1-4 alkyl, halogen, C.sub.1-4 haloalkyl or nitro-group, and/or condensed with a benzene ring; R.sub.1 and R.sub.2 independently mean hydrogen, C.sub.1-4 alkyl, C.sub.1-4 haloalkyl, C.sub.2-4 alkenyl, phenyl, substituted phenyl, C.sub.3-6 cycloalkyl group, R.sub.3 means C.sub.3-6 alkynyl, optionally substituted by one or more C.sub.1-6 alkyl, C.sub.3-6 alkenyl, C.sub.3-6 alkynyl, C.sub.1-6 haloalkyl group, or halogen atom, R.sup.3 also means a C.sub.1-4 alkyloxy-C.sub.1-4 alkyloxy-C.sub.1-4 alkyl group. The process comprises the step of reacting the compounds of general formula II with 1 to 3 molar equivalent of the alcohol of general formula IlI in the presence of acid, a Lewis acid, a metal oxide or a metal carbonate, X means hydroxy, halogen or sulphonester leaving group, the resulting ether of general formula I is isolated, if desired, stabilized by the addition of a base and/or an antioxidant; and if desired the exc…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.