Patent · US Expired

Method and device for determination of concentration

US6321101A · kind A · utility

139Cited by
11References
9Claims
0Family size

Assignee

Inventor

Key dates

Filing dateApr 19, 2000
Grant dateNov 20, 2001
Priority date
Expiry dateApr 19, 2020

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N33/4925
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

In a method and a device for electrochemical determination of the concentration of at least one dissolved chemical entity in a liquid medium, a measurement voltage U is impressed on a working electrode, in contact with the liquid medium, relative to a counter electrode, thereby causing the dissolved chemical entity to react by oxidation or reduction at the working electrode, producing a measurement evoked current. The measurement evoked current is compared to a predetermined value, and the measurement voltage U is adjusted so that the measurement evoked current is substantially equal to the predetermined value, and thus remains substantially constant during measurements. A difference .DELTA.U=U-U.sub.min is formed, which corresponds to an oxidation/reduction reaction at the working electrode, with U.sub.min being a minimum voltage selected as a reference level. This difference is used to calculate concentration variations of the chemical entity in the liquid. A therapy administering apparatus, such as a medical implant such as a pacemaker or the like, can be controlled dependent on the calculated concentration variations.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.