Patent · US Expired

Multipart drug delivery system

US6322815A · kind A · utility

4Cited by

12References

10Claims

0Family size

Inventors

W. Mark Saltzman · New Haven, US
O. Michael Colvin · Baltimore, US
Wenbin Dang · Baltimore, US
Susan M. Ludeman · Delmar, US

Key dates

Filing date	Jul 22, 1994
Grant date	Nov 27, 2001
Priority date	—
Expiry date	Jul 22, 2014

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K47/61
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Polymeric drug conjugates in controlled release matrices are provided which allow sustained concentrations of therapeutic agents within a treated area for a prolonged period. The polymeric drug conjugates hydrolytically degrade in the extracellular space in a controlled, pre-specified pattern, releasing active drug. The conjugates diffuse within the tissue reaching a greater distance from the matrix than free drug would, because of their reduced rate of clearance from the tissue via the capillary system.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.