Patent · US Expired

Method of screening for genetic predisposition to anticholinesterase therapy

US6326139A · kind A · utility

4Cited by

3References

11Claims

0Family size

Assignee

YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. · IL

Inventors

Hermona Soreq · Nesher, IL
Haim Zakut · Savyon, IL

Key dates

Filing date	Oct 6, 1997
Grant date	Dec 4, 2001
Priority date	—
Expiry date	Oct 6, 2017

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/156
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A method of screening for a genetic predisposition to anticholinesterase exposure. The method includes the steps of obtaining a peripheral blood sample, and then analysing serum from the blood sample for BuChE levels and inhibitor-susceptibilities. The DNA of peripheral white blood cells from the blood sample is also screened for the presence of BuChE alleles thereby identifying patients who have a genetic predisposition to anticholinesterase exposure.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.