Assays and peptide substrate for determining aggrecan degrading metallo protease activity
US6326162A · kind A · utility
6Cited by
0References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 24, 1998 |
| Grant date | Dec 4, 2001 |
| Priority date | — |
| Expiry date | Jul 24, 2018 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/102
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention is directed to assays to determine the presence or absence of proteins that exhibit aggrecanase or ADMP activity. This invention also relates to peptides that acts as a substrates for ADMPs, their use in various assays to determine the presence or absence of ADMP activity, and their use as inhibitors of ADMP activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.