Evolution of whole cells and organisms by recursive sequence recombination
US6326204A · kind A · utility
174Cited by
77References
49Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 15, 1998 |
| Grant date | Dec 4, 2001 |
| Priority date | — |
| Expiry date | Jul 15, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/465
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.