Patent · US Expired

Enhanced circulation effector composition and method

US6326353A · kind A · utility

5Cited by

3References

4Claims

0Family size

Assignee

Sequus Pharmaceuticals, Inc. · US

Inventors

Samuel Zalipsky · Redwood City, US
Martin C. Woodle · Bethesda, US
Francis J. Martin · San Francisco, US
Yechezkel Barenholz · Jerusalem, IL

Key dates

Filing date	Mar 23, 1993
Grant date	Dec 4, 2001
Priority date	—
Expiry date	Mar 23, 2013

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S530/812
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A liposome composition comprising small, surface-bound effector molecules is disclosed. The liposomes have a surface layer of hydrophilic polymer chains, for enhanced circulation time in the bloodstream. The effector molecules are attached to the distal ends of the polymer chains. In one embodiment, the effector is polymyxin B, for treatment of septic shock.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.