Dry blend pharmaceutical unit dosage form

US6326384A · kind A · utility

Inventors

• Robert R. Whittle · Wilmington, US
• Frederick D. Sancilio · North Palm Beach, US
• Grayson W. Stowell · Gaylordsville, US
• Douglas John Jenkins · Wilmington, US
• Linda B. Whittall · Wilmington, US

Key dates

• Filing date: Aug 24, 2000
• Grant date: Dec 4, 2001
• Expiry date: Aug 24, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides dry blend pharmaceutical formulations in unit dosage forms comprising per dosage unit one or more active pharmaceutical ingredients or pharmaceutically acceptable salts, solvates, hydrates, or combinations thereof wherein the ratio of said one or more active pharmaceutical ingredients in said formulations is essentially the same as the ratio of said active pharmaceutical ingredients in the corresponding, non-formulated drug substance and, wherein said formulations in unit dosage form are adapted for oral administration.