Delivery system to modulate immune response
US6328967A · kind A · utility
9Cited by
3References
18Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 12, 1998 |
| Grant date | Dec 11, 2001 |
| Priority date | — |
| Expiry date | Mar 12, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A microsphere containing an immunogen bound to an inert particle having a mesh size of greater than about 35 mesh for site-specific release and induction of an immune response. The immune response may be an overall enhanced T lymphocyte immune response or a selective response. The physical and chemical characterigticg and/or modes of administration of the microsphere may be engineered to increase T.sub.H 1 lymphocytes for treatment of cancer or infectious disease. The microencapsulated immunogen has an enteric coating for oral administration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.