Spatially addressable, cleavable reflective signal elements, assay device and method
US6331275A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Aug 3, 2000 |
| Grant date | Dec 18, 2001 |
| Priority date | — |
| Expiry date | Aug 3, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N35/00069
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A cleavable signal element for use in quantitative and qualitative assay devices and methods is described. Binding of the chosen analyte simultaneously to a first and a second analyte-specific side member of the cleavable signal element tethers the signal-responsive moiety to the signal element's substrate-attaching end, despite subsequent cleavage at the cleavage site that lies intermediate the first and second side members. Assay devices comprising the cleavable signal elements are described, as are analytic methods adapted to their use. The analytic devices of the present invention may be adapted to detection using conventional CD-ROM and DVD readers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.