Echinocandine derivatives with antimicrobial activity
US6331521A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 1, 1999 |
| Grant date | Dec 18, 2001 |
| Priority date | — |
| Expiry date | Dec 1, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to new polypeptide compounds represented by the following formula [I]: ##STR1## wherein PA1 R.sup.1 is hydrogen, etc, PA1 R.sup.2 is hydrogen, etc, PA1 R.sup.3 is hydrogen, etc, and PA1 R.sup.4 is hydrogen, etc, or a salt thereof which have antimicrobial activities (especially, antifungal activities), inhibitory activity on .beta.-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for the prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.