Protease inhibitors
US6331542A · kind A · utility
18Cited by
19References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 19, 2000 |
| Grant date | Dec 18, 2001 |
| Priority date | — |
| Expiry date | Apr 19, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/573
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides compounds which inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, and methods for treating diseases of excessive bone loss or cartilage or matrix degradation, including osteoporosis; gingival disease including gingivitis and periodontitis; arthritis, more specifically, osteoarthritis and rheumatoid arthritis; Paget's disease; hypercalcemia of malignancy; and metabolic bone disease, comprising inhibiting said bone loss or excessive cartilage or matrix degradation by administering to a patient in need thereof a compound of the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.