Formulations useful for modulating expression of exogenous genes in mammalian systems, and products related thereto
US6333318A · kind A · utility
58Cited by
25References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 14, 1998 |
| Grant date | Dec 25, 2001 |
| Priority date | — |
| Expiry date | May 14, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In accordance with the present invention, there are provided various methods for modulating the expression of an exogenous gene in a mammalian subject employing modified ecdysone receptors. Also provided are modified ecdysone receptors, as well as homomeric and heterodimeric receptors containing same, nucleic acids encoding invention modified ecdysone receptors, modified hormone response elements, gene transfer vectors, recombinant cells, and transgenic animals containing nucleic acids encoding invention modified ecdysone receptor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.