Methods for normalization of experimental data
US6334099A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 25, 1999 |
| Grant date | Dec 25, 2001 |
| Priority date | — |
| Expiry date | May 25, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B25/00
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
Methods for normalization of experimental data with experiment-to-experiment variability. The experimental data may include biotechnology data or other data where experiment-to-experiment variability is introduced by an environment used to conduct multiple iterations of the same experiment. Deviations in the experimental data are measured between a central character and data values from multiple indexed data sets. The central character is a value of an ordered comparison determined from the multiple indexed data sets. The central character includes zero-order and low order central characters. Deviations between the central character and the multiple indexed data sets are removed by comparing the central character to the measured deviations from the multiple indexed data sets, thereby reducing deviations between the multiple indexed data sets and thus reducing experiment-to-experiment variability. Preferred embodiments of the present invention may be used to reduce intra-experiment and inter-experiment variability. When experiment-to-experiment variability is reduced or eliminated, comparison of experimental results can be used with a higher degree of confidence. Experiment-to-exper…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.