Lipid compounds and compositions containing same used for the transfer of at least an active substance, in particular a polynucleotide, in a target cell and therapeutic use
US6335199B1 · kind B1 · utility
90Cited by
1References
41Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 28, 1998 |
| Grant date | Jan 1, 2002 |
| Priority date | — |
| Expiry date | Oct 28, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/87
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to lipid compounds of formula I, wherein said compounds are optionally in a cationic form and are optionally combined with one or more biologically acceptable anions. The present invention also relates to complexes comprising at least one cationic lipid compound of the formula I and an active substance comprising negative charges. The present invention further relates to methods of gene therapy using the complexes of the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.