Patent · US Expired

Pseudopolymorphic forms of 2-[2-[4-[Bis (4-fluorophenyl) methyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride

US6335331B1 · kind B1 · utility

0Cited by

3References

7Claims

0Family size

Assignee

UCB S.A. · BE

Inventors

Monique Berwaer · Montigny-le-Tilleul, BE
Guy Bodson · Virton, BE
Michel Deleers · Linkebeek, BE
Charles Dogimont · Brussels, BE
Domenico Fanara · Wanze, BE
Jacques Timmermans · Tubize, BE

Key dates

Filing date	Mar 8, 2001
Grant date	Jan 1, 2002
Priority date	—
Expiry date	Mar 8, 2021

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to new pseudopolymorphic forms of 2-[2-[4-[bis (4-fluorophenyl)methyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride, namely, anhydrous 2-[2-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride and 2-[2-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride monohydrate. It also relates to processes for the preparation of these pseudopolymorphic forms and to pharmaceutical compositions containing them.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.