Spiro compounds
US6335345B1 · kind B1 · utility
20Cited by
0References
27Claims
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Assignee
Inventors
Key dates
| Filing date | Aug 14, 2001 |
| Grant date | Jan 1, 2002 |
| Priority date | — |
| Expiry date | Aug 14, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Spiro compounds of the general formula (I): wherein Ar1 represents an optionally substituted aryl or heteroaryl;n represents 0 or 1;T, U, V and W each represent a nitrogen atom or an optionally substituted methine group, wherein at least two of which represent said methine group;X represents methine;Y represents an optionally substituted imino or oxygen atom.These novel spiro compounds exhibit neuropeptide Y receptor (NPY) antagonistic activities and are useful as agents for the treatment of various diseases related to NPY, for example, cardiovascular disorders, central nervous system disorders, metobolic diseases and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.