Pharmaceutical compositions thereof, and methods of using same
US6337316B1 · kind B1 · utility
5Cited by
4References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 13, 1999 |
| Grant date | Jan 8, 2002 |
| Priority date | — |
| Expiry date | Dec 13, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to peptidomimetics capable of inhibiting CD28 and/or CTLA-4 interaction with CD80 (B7-1) and CD86 (B7-2) and having a core amino acid sequence, LeuMetTyrProProProTyrTyr, corresponding to residues 2 to 9 of SEQ ID NO:1. The present invention also relates to pharmaceutical compositions and a method of treating pathologies and disorders which are improved by inhibition of CD28 and/or CTLA-4 interaction with CD80 and CD86.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.