&mgr;-Selective opioid peptides
US6337319B1 · kind B1 · utility
Inventor
Key dates
| Filing date | Oct 2, 1996 |
| Grant date | Jan 8, 2002 |
| Priority date | — |
| Expiry date | Oct 2, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to novel opioid peptides for the treatment of pain as well as a method for the preparation thereof and pharmaceutically acceptable compositions comprising these peptides. The invention also relates to methods for controlling pain in patients using compositions of the invention and the use of said compounds in the preparation of formulations effective in pain treatment. The peptides of this invention have a high degree of selectivity for the &mgr;-opioid receptor. The peptides of the present invention are particularly well-suited as analgesic agents acting substantially on peripheral &mgr;-opioid receptors. Because these peptides act peripherally, they substantially avoid producing side effects normally associated with central analgesic action.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.