Radioprotectant for peptides labeled with radioisotope
US6338835B1 · kind B1 · utility
24Cited by
20References
23Claims
0Family size
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Key dates
| Filing date | Dec 2, 1999 |
| Grant date | Jan 15, 2002 |
| Priority date | — |
| Expiry date | Dec 2, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of ameliorating degradation radiolabeled peptides, especially radiolabeled proteins such as antibodies, by including povidone, also widely known as polyvinylpyrrolidone or PVP, as a radioprotectant in a composition containing a radiolabeled peptide is described. A radioprotectant composition and a stable peptide-radioisotope composition having povidone are also described. Ascorbic acid or other secondary stabilizers may also be added to the compositions to further enhance radioprotection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.