Peptide-lipid conjugates, liposomes and lipsomal drug delivery
US6339069B1 · kind B1 · utility
67Cited by
6References
22Claims
0Family size
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Key dates
| Filing date | Jun 29, 1999 |
| Grant date | Jan 15, 2002 |
| Priority date | — |
| Expiry date | Jun 29, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Peptide-lipid conjugates are incorporated into liposomes so as to selectively destabilize the liposomes in the vicinity of target peptidase-secreting cells, and hence, to deliver the liposomes to the vicinity of the target cells, or directly into the cells. The liposomes can thus be used to treat mammals for diseases, disorders or conditions, e.g., tumors, microbial infection and inflammations, characterized by the occurrence of peptidase-secreting cells.
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