Substituted 4-benzylaminoquinolines and their hetero analogs, process for their preparation, pharmaceuticals containing these compounds and use thereof

US6339077B1 · kind B1 · utility

Assignee

• Aventis Pharma Deutschland GmbH · DE

Inventors

• Armin Hofmeister · Frankfurt, DE
• Eugen Falk · Frankfurt am Main, DE
• Heinz-Werner Kleemann · Bischofsheim, DE
• Hans-Willi Jansen · Niedernhausen, DE
• Martin Bickel · Frankfurt am Main, DE

Key dates

• Filing date: Sep 22, 2000
• Grant date: Jan 15, 2002
• Expiry date: Sep 22, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07J41/0061
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to substituted 4-benzylaminoquinolines and their hetero analogs, and to the pharmaceutically acceptable salts and physiologically functional derivatives thereof. Compounds of formula I in which the radicals are defined in the specification, and their physiologically tolerated salts, physiologically functional derivatives and processes for their preparation are described. The compounds are suitable, for example, as medicines for the prophylaxis or treatment of gallstones.