Microencapsulated and controlled-release herbal formulations
US6340478B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 7, 1999 |
| Grant date | Jan 22, 2002 |
| Priority date | — |
| Expiry date | Jun 7, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/2081
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There is provided an orally-administrable formulation for the controlled release or stable storage of a granulated herb, comprising a granulated herb and at least one carrier, adjuvant or excipient therefor. Preferably, the formulation is characterized in that the total in vitro dissolution time of said formulation required for release of 75% of the active ingredients available from the formulation is between about 4 and about 18 hours, as determined by the U.S.P. XXIII paddle method at a paddle speed of 150 rpm, using simulated intestinal fluid without the digestive enzymes normally found in intestinal fluid, containing 0.1% w/w sodium dodecyl sulfate (SDS), at pH 6.8, and a temperature of 37° C. A process for the preparation of such formulation is also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.