Nucleic acid molecules related to card-4L and CARD-4S
US6340576B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Jun 17, 1998 |
| Grant date | Jan 22, 2002 |
| Priority date | — |
| Expiry date | Jun 17, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/4702
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Novel CARD-3, CARD-4L and CARD-4S polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, CARD-3, CARD-4L and CARD-4S proteins, and the invention further provides isolated CARD-3, CARD-4L and CARD-4S fusion proteins, antigenic peptides and anti-CARD-3, anti-CARD-4L and anti-CARD-4S antibodies. The invention also provides CARD-3, CARD-4L and CARD-4S nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a CARD-3, CARD-4L or CARD-4S gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.