Deprotection and recrystallization processes
US6340752B1 · kind B1 · utility
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10Claims
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Key dates
| Filing date | Dec 9, 1998 |
| Grant date | Jan 22, 2002 |
| Priority date | — |
| Expiry date | Dec 9, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D223/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Acylmercaptoalkanoylamino lactam esters or acids are converted to the corresponding mercaptoalkanoylamino lactam ester or acid under basic conditions by including an agent which minimizes the amount of disulfides. Suitable agents are bismercaptans, phosphine or phosphite reducing agents, zinc metal powder, and sodium hydrosulfite. Such agents are also employed in the recrystallization and reprocessing of the mercaptoalkanoylamino lactam acids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.